Review article: tegaserod for chronic constipation
نویسندگان
چکیده
منابع مشابه
Review: good evidence supports polyethylene glycol and tegaserod for constipation.
M e t h o d s Data sources: MEDLINE (1966 to 2004) and bibliographies of relevant studies and reviews. Study selection and assessment: Randomized controlled trials (RCTs) that compared medical therapies with placebo or compared 2 separate agents in adults with constipation. Quality assessment of individual studies was done using a 5-point scale (5 = highest quality) and included randomization p...
متن کاملReview article: tegaserod -- the global experience.
Studies from the Western hemisphere have established the efficacy and safety of tegaserod in women with irritable bowel syndrome and constipation. This review summarizes the results of recent studies from around the world that confirm the efficacy and safety of tegaserod, and expand our understanding of the role of this drug in the treatment of patients with irritable bowel syndrome.
متن کاملTegaserod for the treatment of irritable bowel syndrome and chronic constipation.
BACKGROUND IBS is a complex disorder that encompasses a wide profile of symptoms. The symptoms of chronic constipation frequently resemble those of constipation-predominant IBS. Current drug treatments for irritable bowel syndrome (IBS) are of limited value. Many target specific symptoms only. Tegaserod, a 5HT(4) partial agonist, represents a novel mechanism of action in the treatment of IBS an...
متن کاملReview: good evidence supports use of polyethylene glycol and tegaserod for constipation.
Ramkumar D, Rao SS. Efficacy and safety of traditional medical therapies for chronic constipation: systematic review. Am J Gastroenterol 2005;100:936–71. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....
متن کاملSafety and efficacy of tegaserod therapy in patients with irritable bowel syndrome or chronic constipation.
BACKGROUND Tegaserod, a 5-HT4 agonist, is effective for treating irritable bowel syndrome and chronic constipation. However, sales of this drug were recently suspended due to concerns about a higher rate of cardiovascular events in patients receiving tegaserod over placebo in clinical trials. Our aim was to review patients in our practice prescribed tegaserod to determine if any of them had suf...
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ژورنال
عنوان ژورنال: Alimentary Pharmacology & Therapeutics
سال: 2004
ISSN: 0269-2813
DOI: 10.1111/j.1365-2036.2004.02187.x